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Pepperl S, Drger M, Ringel F et al (2001) Hyperoxia upregulates the NO pathway in alveolar macrophages in vitro: role ofAP-1 and NF-kappaB

10.1016/j.jpeds.2013.11.040 195
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Moreover, free radicals also interfere with electron transport chain (ETC) complexes, further promoting ROS generation (41)

Intravenous glutathione can boost energy, well-being, and alertness for a period of one to several days

As the use of contemporary neuroscience techniques such as optogenetics and circuit-specific genetic manipulations become more widespread, enhanced understanding of how specific circuits control behaviors will provide opportunities to target GPCRs that modulate critical addiction circuitry to correct pathological drug use
