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Based on our histopathological and biochemical findings, we propose a mechanistic model illustrating the neuroprotective effects of anakinra following cardiac arrest (Fig

The powders demonstrated increased ciliary beat frequency, improved mucociliary clearance, preserved epithelial integrity, and minimal cytokine release in vitro , restored tracheal mucus velocity in a dose-dependent manner in sheep, and confirmed safety with an established a no observed adverse effect level of 2.32 mg/kg/day that provides a 11.6-fold safety margin over a human dose of 50 mg/day on a mg/g of lung weight basis

2021, 118 (37), e2103280118 DOI: 10.1073/pnas.2103280118Google ScholarThere is no corresponding record for this reference

& Fawzi, N

Thirdly, and serendipitously, the apo structures also reveal the conformation of the crucial C-terminal region that is disordered in all previous apo structures