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Three weeks of 0.12% TMAO supplementation during weaning in C57BL/6 and Apoe / mice significantly increased the expression of scavenger receptors CD36 and SR-A1 in peritoneal macrophages compared to a normal chow diet (53)

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stling P, Leivonen SK, Aakula A, Kohonen P, Mkel R, Hagman Z, Edsj A, Kangaspeska S, Edgren H, Nicorici D, et al

This improves glucose uptake in muscle cells and regulates glucose levels, which enhances insulin action and reduces markers of inflammation and oxidative stress, factors associated with diabetes

Overall, muscle regeneration following injury is promoted by AX through multiple mechanisms, including the modulation of cellular differentiation and the enhancement of mitochondrial biogenesis, which together contribute to improved cell survival