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Drugs and some fatty acids can be targeted by this conjugation reaction, resulting in the conjugated product usually being excreted by the liver in the bile

It should be noted that measurements of glutamate in CSF are likely to give better approximation of glutamate concentrations at synapses than are plasma glutamate concentrations

The proposed mechanisms are not all consistently supported by independent replication, and the molecular target(s) responsible for the observed effects have not been definitively identified

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