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The amounts produced during roasting are variable, but generally speaking, norharman increases during roasting and harman decreases after 240C (464F) (Casal, 2015)

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This can cause damage to cells and tissues, leading to chronic inflammation. The activation of the Nrf2 pathway by sulforaphane reduces oxidative stress in a clever variety of ways, including pumping out more glutathione to neutralise free radicals, thereby reducing inflammation

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