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However, no published clinical trials exist specifically on acetyl-L-carnitine for leg cramps [7]

Moreover, despite elevated TMAO, LC supplementation together with resistance training induced positive changes in mitochondrial DNA methylation of platelets [18]

Este efecto es an ms pronunciado en las personas mayores, ya que los niveles generales de L-carnitina disminuyen con la edad

An early study showed that 250 M acetyl-l-carnitine did not affect axon regeneration but significantly reduced the rate of death of neurons from the DRG of aging rats, suggesting its neuroprotective action [14]

(Hershman (2018): As a result of this evidence, current clinical guidelines advise against the use of acetyl-L-carnitine for CIPN prevention