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409,410,419425 Early structural work on Pa Fur 426 and Vc Fur 416 revealed that Fe II and other divalent metals could allosterically activate DNA binding by altering the metalation status of one or both of the two regulatory sites observed (Figure 14B)

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Preventing Diabetic Ketoacidosis (DKA) Monitor the patient for signs and symptoms of DKA, including hyperglycemia, dehydration, electrolyte imbalances, and acidosis