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GST isoforms mu and pi have been identified as overexpressed in Alzheimer's disease

In contrast, GPx-1-overexpressing mice are partially protected from dopaminergic damage in response to 6-hydroxydopamine-induced toxicity (29)

Glucagon-like peptide-1 inhibits prandial gastrointestinal motility through myenteric neuronal mechanisms in humans

The two are structurally unrelated and act through different biological pathways, which is the main reason researchers became interested in studying them in combination

[DOI] [PMC free article] [PubMed] [Google Scholar] 276.Zeng A., Liang X., Zhu S., Liu C., Wang S., Zhang Q., Zhao J., Song L