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Pharmacologic or genetic manipulation of glutathione S-transferase P1-1 (GSTpi) influences cell proliferation pathways

The rise in popularity of curcumin has led to an increased availability of dietary supplements promoted for their antioxidant and anti-inflammatory benefits [60, 61]

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While transient activation can protect genomic stability, prolonged or context-dependent expression may confer survival advantages to malignant cells under therapy-induced stress

Biochem J (2017) 474(12):193563.10.1042/BCJ20160822 18 ChiotellisAMullerAWeyermannKLeutwilerDSSchibliRAmetameySMet alSynthesis and preliminary biological evaluation of O-2((2-[(18)F]fluoroethyl)methylamino)ethyltyrosine ([(18)F]FEMAET) as a potential cationic amino acid PET tracer for tumor imaging