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Microb Ecol Health Dis

Large animal models also proved their uniqueness due to specific anatomical and physiological characteristics pertinent to those specific researches (Liao et al

doi: 10.1016/0076-6879(90)86134-H

Mitochondrial dysfunction leads to the accumulation of unfolded or misfolded proteins, which can be recognized by molecular chaperones and transported to the nucleus to induce the activation of the corresponding transcription factors and repair mitochondrial damage (Sutandy et al
