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42 Additionally, ATP production from normal mitochondrial respiration negatively regulates mitochondrial NOX4-induced ROS production through direct interaction between ATP and the NOX4 Walker A binding motif, 43 which suggests mitochondrial NOX4 may play a dynamic role in metabolic function

Silver nanoparticles also have anti-inflammatory effects because they modulate the expression of metallo-proteinase substrates, which are important proteolytic enzymes in various inflammatory and repair processes (Nadworny et al

doi: 10.1016/J.LFS.2019.05.029 57

10.1111/jcmm.15009 69 HensleyC

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