igf 1 lr3 cause cancer GH and IGF1 in therapy resistance in: Endocrine-Related Cancer Volume 30 Issue 9 (2023) Insulin-Like Growth Factor (IGF) Pathway

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Post-translational modifications of specific mitochondrial proteins, such as ubiquitination of Myro2, increased SUMOylation of DRP1, decreased SUMOylation of mitofusins (MFN2), phosphorylation of DRP1, or alterations in their expression levels, such as excessive increase or deficiency of PGC1-alpha, increased levels of DRP1, reduced expression of MFN2 or OPA-1, leads to several heart diseases (Fan et al., 2020)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 55.Zhou J, Li X Y, Liu Y J, et al