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Another stress mitigation tool that drew Hubermans attention was even more ancient, wired into mammalian biology

Acknowledgements This work was supported by the US National Institutes of Health (NIH) grant (R35 CA197588), Stand Up to CancerAmerican Association for Cancer Research grant (SU2C-AACR-DT22-17), and the Damon Runyon Cancer Research Foundation

Immunology courses already taken

Zhang H, Court N, Forman HJ

A prominent example is their inhibition of the PI3K/Akt pathwayGA treatment in lung cancer cells led to downregulation of PI3K/Akt alongside increased p53 levels, which in turn activated downstream executioner caspases and cell cycle inhibitors (p21Cip1/p27Kip1), culminating in apoptosis and growth arrest (151)