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But people can get blemishes from flu shots, so there is no direct correlation that B12 causes blemishes. Unfortunately though, theres no way to know beforehand if B12 will cause a breakout

Kheiridoost H, Shakouri SK, Shojaei-Zarghani S, Dolatkhah N, Farshbaf-Khalili A

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243 In addition, the lncRNA SPRY4 intronic transcript 1 (SPRY4-IT1) similarly enhanced the intestinal epithelial barrier function through augmenting the expression of mRNAs encoding CLDN1, CLDN3, and JAM-1

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