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Treatments took place approximately two weeks apart

Do not use if the solution is cloudy or contains debris.

Therefore, the aim of this study was twofold: 1) to assess vitamin B12 serum levels in ME/CFS patients before and after use of high dose vitamin B12 nasal drops and 2) to compare the changes in function before and after starting therapy, using an activity meter, the physical functioning score of the Rand 36 questionnaire, and both the fatigue and concentration scales of CIS20r questionnaire

This could be monthly injections for those with absorption issues, or less frequently if you're just topping up levels
