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Conversely, T cell-specific FXR deletion improved survival and reduced T cell IFN production, suggesting FXR can transcriptionally promote T cell effector functions in certain inflammatory settings (88)

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Parkinson's disease (PD) PD is the second most common neurodegenerative disease following AD, and is associated with the loss of dopaminergic neurons in the Substantia Nigra compacta (SNc)