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This phased structure reduces the likelihood of toxin recirculation and improves tolerability by prioritizing containment and clearance rather than intensity
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A consistent extract composition facilitates research of its pharmacology with pharmacokinetics describing compound concentrations at specific body sites and pharmacodynamics elucidating bioactivities on a cellular or clinical level

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Moskowitz A, Huang DT, Hou PC, Gong J, Doshi PB, Grossestreuer AV, Andersen LW, Ngo L, Sherwin RL, Berg KM, Chase M, Cocchi MN, McCannon JB, Hershey M, Hilewitz A, Korotun M, Becker LB, Otero RM, Uduman J, Sen A, Donnino MW, Investigators ACT (2020) Effect of ascorbic acid, corticosteroids, and thiamine on organ injury in septic shock: the ACTS randomized clinical trial