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Oncotarget 9 , 3228032297 (2018)
Despite extensive biochemical knowledge of cobalamin metabolism and its physiological importance, the optimal supplementation route for maintaining or restoring adequate vitamin B12 levels remains debated
Yan W, et al

The dissolution time can vary depending on individual factors, but generally, the troche should dissolve slowly over a period of 15-30 minutes

A 1000 g injection can result in the retention of up to 150 g in the vast majority of patients in very severe and advanced cases