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Yoda1 binds allosterically to A pocket about 40 A from the central pore and acts as a molecular wedge to facilitate force-induced conformational changes by lowering the mechanical activation threshold of the channel (Botello-Smith et al., 2019)

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The growth hormone connection also helps explain BPC-157s effects on muscle tissue

All real-time PCRs were performed three times and all changes in gene expression were reported as multiples of increases relative to the control while GAPDH was used as an internal control and relative gene expression between the experimental groups were determined using MxPro software