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doi: 10.2147/ott.S228453 71 MaciejczykASurowiakP

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Given AKT1s established role in insulin signaling, mitochondrial function, and energy metabolism, its upregulation may explain key pathological features of lipedema, including impaired oxidative phosphorylation, chronic inflammation, and altered adipocyte metabolism

All of these adopt a segmentation-binding mode like that of LMNG, which permits specific molecules to enter or exit