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Adv Sci (Weinh)

The paper remains the most-cited single source for GHK-Cus pleiotropic gene-expression effects and is a primary reference for the compounds research applications in dermal aging, wound healing, and oxidative stress models

The increased reactive oxygen species (ROS) levels, including superoxide, hydrogen peroxide, and hydroxyl radicals, can damage lipids, proteins, and DNA, disrupting cellular function and structure

Aconitase and succinate dehydrogenase activities are markedly reduced and mitochondrial iron overload develops in patient muscle samples [54] (Box 1)

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