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Other CRISPR studies have identified candidate susceptibility loci in detoxification pathways, including GSTM1, CYP1A1, and NQO1

ER, endoplasmic reticulum

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Sharma SK, Bhatt P, Asdaq SMB, et al

Mitochondrial dna depletion, oxidative stress, and mutation: mechanisms of dysfunction from nucleoside reverse transcriptase inhibitors
