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106 : 483491 Starkebaum G and Harlan JM (1986) Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine

doi: 10.1111/pce.13617 75 LeshemY

While there is good evidence to support this idea in model organisms such as Drosophila melanogaster and Caenorhabditis elegans , [68] [69] recent evidence from Michael Ristow's laboratory suggests that oxidative stress may also promote life expectancy of Caenorhabditis elegans by inducing a secondary response to initially increased levels of reactive oxygen species

In fact, SFN alone may also act as an oxidative stressor in cells

The immune system