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Benzo(a)pyrene-induced acute neurotoxicity in the F-344 rat: role of oxidative stress

They are essential for detoxification and metabolism of drugs

Additionally, it has been demonstrated that the combination of docetaxel and R162 inhibits the development and metastasis of non-small cell lung cancer cells resistant to docetaxel, hence bolstering the effectiveness of combination therapy including anticancer medications and GLUD1 inhibitors as a cancer treatment approach [111]

This Research Topic is part of a series with: The changing faces of glutathione, a cellular protagonist., Volume II Glutathione (GSH) has been described for a long time just as a defensive reagent against the action of toxic xenobiotics (drugs, pollutants, carcinogens), both directly and as a cofactor for GSH transferases
