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It would be interesting for future research to determine if this overgrowth may worsen brain fog symptoms by disturbing the normal microbiome [87]

Metformin protects against diabetes-induced cognitive dysfunction by inhibiting mitochondrial fission protein DRP1

Inhibition of GAPDH and overall prolonged suppression of glycolysis, as marked by decreased glucose utilization and lactate [113], have also been noted

With that drop in total intake comes a corresponding drop in: Fiber Fluid Magnesium, potassium, and other motility-supporting nutrients This creates the perfect storm for sluggish bowels

This indirectly increases mitochondrial biogenesis and promotes the migration of OS cells (111)