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Synthesis Add 96g of acetic acid to the reaction vessel, add 32g of levulinic acid to dissolve under stirring, when completely dissolved, add 61.5g of acetic anhydride, then raise the temperature to 80 constant temperature reaction for 12 hours, the reaction is completed, in a vacuum of -0.09Mpa, the temperature of 80 below the distillation of acetic acid removal, reduce the temperature to 40 , add 160g of acetone, fully stirred and dispersed for 0.5 hours, reduced temperature to 5 below precipitation of crystals, and held between 0 ~ 5 for 2 hours, filtration and separation, wash the solid with acetone, in a vacuum -0.09 Mpa, dried at 80 , that is to obtain acetyl levulinic acid 36g finished product, yield 88.9%

Species-specific endotoxin stimulus determines toll-like receptor 4- and caspase 11-mediated pathway activation characteristics

237: 1310-1321 76 Gao X, Liu X, Xu J et al

Daten geben Mittelwerte (Standardabweichungen) an, auer bei anderen Angaben

It has been shown to improve mental focus, memory, and overall brain function