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Carney, S

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Once the regulatory signals have been delivered, the body maintains the improved function for extended periods before another course may be needed

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Therefore, in the treatment of gastrointestinal diseases, dihydrocurcumin may be more effective in treating small bowel injuries, such as those caused by nonsteroidal anti-inflammatory drugs or radiation, and terminal ileitis (Crohn's disease), while curcumin and tetrahydrocurcumin are more effective in treating cecal injuries, such as appendicitis and cecal cancer