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The resulting hexapeptide specifically and dose-dependently released GH both in vitro and in vivo through a mechanism entirely distinct from growth hormone-releasing hormone (GHRH)

The amount of HGF inhibitor that is administered may be in the range of from about 0.1 to about 1 ,000 mg/kg, an preferably in the range of from about 1 to about l OOmg/kg, although as one of skill in the art will recognize, the precise amount may vary depending on one or more attributes of the drug recipient, including but not limited to: weight, overall health, gender, age, nationality, genetic history, other conditions being treated, etc., and larger or smaller doses are within the practice of this invention

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Interestingly, TIMP-2 knock out mice show deficits in fear potentiated startle (65)

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