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Hypoxia enhances HIF-1 which up-regulated TfR and DMT1 to increase iron uptake, which effects the sensitivity of cells to ferroptosis (Xiong et al

Future Considerations We seek to develop a comprehensive set of quality measures to be available for widespread use for informed decision-making and quality and cost improvements focused on the inpatient hospital setting

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Practically, this means the ODT requires higher doses to achieve comparable effects, and individual responses will vary more than with injections