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Different areas have different tissue depths, nerve densities, and proximity to blood vessels

Initial response time also depends on: Severity of the B12 deficiency Frequency of injections Underlying health conditions Absorption and metabolism differences If youre getting your first B12 shot, your provider may start you on a more aggressive schedule, such as weekly injections until your levels are normalized

If you are prone to cold sores we may want to institute antiviral therapy before injecting the lips

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