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Disruptions in brain insulin signaling can adversely affect the dopaminergic mesolimbic reward circuit, altering hedonic perceptions [89, 90]
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Furthermore, it is easily dissolved in water and needs no carrier for its application
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Note that BPC 157, given in the reperfusion, showed a strong therapy effect in rats with the Pringle maneuver [10], stroke [17], spinal cord compression [37,38], and ischemic/reperfusion ulcerative colitis [39]
