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PEG-IFN/RBV during 24 weeks in untreated HCV-3 patients achieved an identical SVR12 rate of 67% in HCV-3 patients with both regimens.[89] Mericitabine (RG7128) is a nucleoside polymerase inhibitor, with anti-viral activity demonstrated in vitro against all HCV genotypes

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doi: 10.4081/cp.2011.e17

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preparing (R)-4-chloro-3-hydroxy butyric acid alkyl ester of Formula 4 from stereoselective hydrolysis of the racemic 4-chloro-3-hydroxy butyric acid alkyl ester of Formula 3 in an aqueous solution using an enzyme or an enzyme- containing microorganism

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