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[DOI] [PubMed] [Google Scholar] 53.Knight TF, Sansom SC, Senekjian HO, Weinman EJ

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Elevated ROS levels disrupt antioxidant defenses, including glutathione peroxidase 4 (GPX4) activity and the cystine/glutamate antiporter system (xCT), thereby disturbing redox homeostasis and promoting lipid peroxidation and ferroptosis-related cellular damage

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