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mtDNA is 10 times more vulnerable to mutations and oxidative stress than nDNA due to a lack of histones protection, fewer repair enzymes, and increased susceptibility to supercoiling damage [94]

JCI Insight 5, 134539

G.lvarezV.MatillaE.et al (2018)

Induction of immunological tolerance by apoptotic cells requires caspase-dependent oxidation of high-mobility group box-1 protein

The spiral ganglion was embedded within the modiolus and contained the cochlear nerve neurons (Fig