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The ultra-long half-life may eliminate the need for dose titration, which would be a significant convenience advantage over current GLP-1 therapies
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Systemic injection (lower abdomen or upper thigh) supplements it
For flash freezing the crystal was harvested into a cryogenic liquor containing 100 mM Tris-HCl pH 7.5, 0.15 M KBr, 17% (w/v) PEG 3350, 25% (w/v) PEG 400
The shot delivers a high dose of therapeutic B12, usually in the form of cyanocobalamin or hydroxocobalamin
