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In a recent study, the researchers combined the high specificity of the methylation-sensitive restriction enzyme GlaI for methylase digestion with the high amplification efficiency of rolling circle amplification (RCA) to detect GlaI digestion products

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10, 11 Moreover, the pharmacological antioxidant N -acetylcystein (NAC) enhances T-cell function and proliferation by inhibition of nuclear factor- B (NF- B)

The establishment of comprehensive lactylation maps in various systems by proteomics and modification omics, particularly in human and mouse cells, would substantially advance the field of protein lactylation research, enhancing our comprehension of its functions