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Coordinated control of cholesterol catabolism to bile acids and of gluconeogenesis via a novel mechanism of transcription regulation linked to the fasted-to-fed cycle

Collectively, these findings confirm that zebrafish are highly effective for elucidating the multi-target mechanisms of diverse phytochemicals, encompassing regulation of redox balance, modulation of inflammatory mediators, and control of central signaling pathways such as NF-B , MAPK , and Nrf2 (Table 3)

Omega-3 supplementation can restore glutathione levels and prevent oxidative damage caused by prenatal ethanol exposure

J Clin Invest 1963;42:1816 1834