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This dysfunction manifests as reduced vascular response to dilators (particularly to NO and prostacyclin), heightened pro-inflammatory responses leading to vascular wall inflammation, increased oxidative stress contributing to vascular damage, and pathological changes

Intranasal deferoxamine provides increased brain exposure and significant protection in rat ischemic stroke

Begum, N

[DOI] [PubMed] [Google Scholar] 327.Luna-Flores C.H., Wang A., von Hellens J., Speight R.E