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To treat AD, thirteen new oxathiolanyl, pyrazolyl, and pyrimidinyl indole derivatives were created and produced
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Meanwhile, GSH preservation in cytosolic and mitochondrial fractions downregulates the expression of RIPK1, RIPK3, or MLKL, preventing necrosome formation 74,75
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Interestingly, IGF-I is somehow related to all of them (Figure3)
