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3.1 Inflammatory respiratory diseases NSPs are released in the airways of patients with multiple types of chronic pulmonary diseases such as COPD, AATD, bronchiectasis, and CF, and have been implicated as key mediators of chronic inflammation and disease progression (59)

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De Lima and Mortari, 2022), morphology (Song et al., 2021), surface charge and modification (Kulkarni and Feng, 2013