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Accessed at ncbi.nlm.nih.gov/books/NBK548087 on December 11, 2023

FMO3 is the member of the FMO enzyme family with the highest activity level and is capable of oxidizing TMA to TMAO

Fitzgibbon BM, Hoy KE, Knox LA, Guymer EK, Littlejohn G, Elliot D, Wambeek LE, McQueen S, Elford KA, Lee SJ, Enticott PG, Fitzgerald PB (2018) Evidence for the improvement of fatigue in fibromyalgia: A 4-week left dorsolateral prefrontal cortex repetitive transcranial magnetic stimulation randomized-controlled trial

Fasting baseline TMAO levels were significantly lower among vegan/vegetarian subjects compared to omnivores (Fig

Cognitive function is partially improved in Mecp2 null mice early, but not late in life with ALC treatment Ideally, a therapy would ameliorate the severe cognitive deficits associated with RTT in addition to improving general health, metabolic, and basic motor function
