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TABLE 1 Describes the effect of antidiabetic drugs on the action of ROS

If intranasal bioavailability is 10% relative to subcutaneous, a 10-fold higher nasal dose would be needed to match exposure, but ceiling effects, tolerability, and mucosal volume limits complicate this further

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Florey Department of Neuroscience and Mental Health, The University of Melbourne, Melbourne 3010, Australia
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