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Arch Biochem Biophys 1989, 268: 393-397

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doi:10.1016/j.ajpath.2010.10.007 Yoshida T, Delafontaine P

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It also enhances the efficacy of standard chemotherapies (e.g., 5-fluorouracil and paclitaxel) through synergistic mechanisms involving oxidative stress and apoptosis pathways

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Rather than a series of short spikes, the long-acting form keeps a gentle, ongoing prompt in place

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