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FIGURE 10 Oxidative stress, associated with high dose MTX, triggers a systemic inflammatory response where proinflammatory cytokines further contribute to tissue damage (Kalantar et al., 2019a

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Waters, Milford, MA) were equilibrated with 6 mL methanol and 2 mL H 2 O before samples were loaded onto columns

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SD, Stargardts disease

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Due to its chemical profile as a pro-oxidant that metabolizes to a second antimicrobial substance (i.e., DDTC), the mechanisms of action of DSF are believed to differ from those of classical antibiotics

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Argyri AA, Papadopoulou OS, Sourri P, Chorianopoulos N, Tassou CC

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