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Patch-clamp experiments in HEK293 cells expressing 122 GABA_A receptor subunits have revealed that apigenin inhibits GABA-evoked chloride currents, albeit with less potency compared to classical benzodiazepines

Garcia C, Pithon-Curi TC, de Lourdes Firmano M, Pires de Melo M, Newsholme P, Curi R

De novo assembly of polyploid genomes is challenging due to the presence of multiple subgenomes, high heterozygosity and complicated assembly of repetitive sequences 53,54

Quercetin and structurally related flavonoids demonstrate inhibitory activity against cytochrome P450 isoenzymes (notably CYP3A4) alongside P-glycoprotein-mediated efflux mechanisms (304, 305)

Inflamm-ageing: the role of inflammation in age-dependent cardiovascular disease