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According to the guidelines of the International Pediatric Sepsis Consensus Conference 104 , neonatal sepsis is defined as a clinical syndrome characterized by the presence of both infection and systemic inflammatory response syndrome (SIRS) and can cause severe neurological complications due to brain infection, as well as secondary hypoxemia resulting from septic shock, pulmonary hypertension and severe lung disease

Espn E, Yang C, Shannon CP, Assadian S, He D, Tebbutt SJ

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The result can range from mild discomfort to debilitating pain that radiates down the legs

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