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If these free radicals accumulate, they cause oxidative stress , which can damage cellular structures, including proteins and DNA

Nat Rev Cancer 8:96775 Orrenius S, Gogvadze V, Zhivotovsky B (2007) Mitochondrial oxidative stress: implications for cell death

But the story becomes much more complicated when you look closely at the evidence

Exploring the structure and activity of haloalkane dehalogenase from Sphingomonas paucimobilis UT26: evidence for product- and water-mediated inhibition
