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Disc herniation involves both mechanical factors (the displaced disc material) and biochemical factors (inflammation)

Finally, therapeutic opportunities and ongoing preclinical/clinical studies targeting these pathways are comprehensively evaluated

While the etiology is multifactorialinvolving genetic susceptibility, environmental triggers, and gut microbiota dysbiosisthe terminal event in IBD pathology is the compromise of the intestinal epithelial barrier

The characteristics of small molecules used as assembly components can fundamentally affect the physicochemical properties and biological effects of the self-assembled system

High-throughput screening and automation, as well as artificial intelligence-based strategies, can be used to identify novel ferroptosis modulators and the underlying mechanisms