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These include variability in dosing, reported adult dosages range from 30 to 300 mg/day, depending on the clinical indication, formulation, and treatment duration, and the lack of standardized dosing regimens, which complicates cross-study comparisons ( In the near-term, PYC is most likely to serve as an adjunctive or nutraceutical support rather than a standalone therapeutic agent

(More information) Severe deficiency in either folate or vitamin B 12 can lead to megaloblastic anemia, which causes fatigue, weakness, and shortness of breath

Dependence and Withdrawal: Risk of psychological dependence and withdrawal symptoms upon cessation

Rodriguez-Pasamontes C
