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Third, ferroptosis inducers, while targeting tumor cells, may inadvertently impact immune cells in the TME, potentially compromising the immune response and attenuating overall antitumor efficacy

[DOI] [PMC free article] [PubMed] [Google Scholar] 122.Bharucha, A

This resistance is often tied to changes within fat cells themselves, including the activity of a key metabolic enzyme known as NNMT

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